Ukr.Biochem.J. 2015; Volume 87, #2, March-April

Fatty acid composition of phospholipids and esterified cholesterol of the blood plasma of rabbit under arginine acute pancreatitis

29.05.2015   Без рубрики   No comments

O. O. Hopanenko, J. F. Rivis

Institute for Agriculture Region of Carpathian, National Academy of Agricultural Sciences, Lviv;
e-mail: hopanenko@gmail.com

The content and fatty acid composition of phospholipids and esterified cholesterol were studied in the blood plasma of rabbits under acute arginine pancreatitis and its correction using linseed oil. It is established that the transport and anti-inflammatory functions of blood plasma deteriorates under acute arginine pancreatitis due to a decrease of the content of polyunsaturated fatty acids in phospholi­pids. The amount of cholesterol esterified with saturated and monounsaturated fatty acids increases in the blood plasma of rabbits. The concentration of phospholipids­ and esterified cholesterol is normali­zed and their fatty acid composition is improved in the lipid composition of the blood plasma of rabbits with acute arginine pancreatitis fed with linseed oil.

Ключевые слова: , , , , , ,

Ссылки:

  1. Singh VK, Wu BU, Bollen TL, Repas K, Maurer R, Mortele KJ, Banks PA. Early systemic inflammatory response syndrome is associated with severe acute pancreatitis. Clin Gastroenterol Hepatol. 2009 Nov;7(11):1247-51. Epub 2009 Aug 15. [pm id="19686869"], [cr id="http://dx.doi.org/10.1016/j.cgh.2009.08.012"]
  2. Mayerle J, Simon P, Lerch MM. Medical treatment of acute pancreatitis. Gastroenterol Clin North Am. 2004 Dec;33(4):855-69, viii. Review. [pm id="15528022"]
  3. Windsor AC, Kanwar S, Li AG, Barnes E, Guthrie JA, Spark JI, Welsh F, Guillou PJ, Reynolds JV. Compared with parenteral nutrition, enteral feeding attenuates the acute phase response and improves disease severity in acute pancreatitis. Gut. 1998 Mar;42(3):431-5. [pm id="9577354"], [pmc id="PMC1727034"]
  4. Zhang X., Qi R., Xian X., Wang Y., Huang W., Liu G. Atherogenesis, pancreatitis and brain dysfunction in LPL deficient mice with severe hypertriglyceridemia. Atheroscler. Suppl. 2008;9(1):29. [cr id="http://dx.doi.org/10.1016/s1567-5688(08)70109-0"]
  5. Naito Z, Ishiwata T, Lu YP, Teduka K, Fujii T, Kawahara K, Sugisaki Y. Transient and ectopic expression of lumican by acinar cells in L-arginine-induced acute pancreatitis. Exp Mol Pathol. 2003 Feb;74(1):33-9.[pm id="12645630"], [cr id="http://dx.doi.org/10.1016/s0014-4800(03)80006-0"]
  6. Pryvroczka I. B., Pokotylo O. S. The evolution of the pro- and antioxidant balance in acute pancreatitis and its correction. Eksperymentalna ta Klinichna Fiziologiya i Biokhimiya. 2011;2:42-47. (In Ukrainian).
  7. Girard-Mauduit S. The lipid triad, or how to reduce residual cardiovascular risk? Ann Endocrinol (Paris). 2010 Mar;71(2):89-94. Epub 2010 Mar 19. [pm id="20303470"], [cr id="http://dx.doi.org/10.1016/j.ando.2010.02.001"]
  8. Kozachok M. M., Osodlo G. V., Kucz T. V. The role and place of essential phospholipids in the treatment of chronic diffuse liver diseases. Suchasna Gastroenterologiya. 2006;30(4):95-101. (In Ukrainian).
  9. Rivis J. F., Fedoruk R. S. Quantitative chromatographic methods for determination of various classes of lipids and fatty acids in biological material. Lviv: Spolom, 2010; 109 p. (In Ukrainian).
  10. Lopach S. N., Chubenko A. V., Babych P. N. Statistical methods in biomedical studies using Excel. K.: Mоrіon, 2001; 408 p. (In Russian).
  11. Edwards P. A., Davies R. Isoprenoids: sterols and bile acids. In: Biochemistry of lipids, lipoproteins and membranes. Amsterdam: Elsevier Science В. V. 1996:341-360.
  12. Dlyaboga Yu. Z., Rivis J. F. Phospholipid fatty acid composition of plasma , liver and skeletal muscle of rats by experimental hypercholesterolemia and impact of fish oil. Biologichni Studiyi. 2011;5(2):73-85. (In Ukrainian).
  13. Fernandez ML, West KL. Mechanisms by which dietary fatty acids modulate plasma lipids. J Nutr. 2005 Sep;135(9):2075-8. Review. [pm id="16140878"]
  14. Crawford M, Galli C, Visioli F, Renaud S, Simopoulos AP, Spector AA. Role of plant-derived omega-3 fatty acids in human nutrition. Ann Nutr Metab. 2000;44(5-6):263-5. [pm id="11146334"], [cr id="http://dx.doi.org/10.1159/000046694"]
  15. Cyupko V. V. Structure and significance of polyunsaturated fatty acid metabolism in humans and animals. Biologiya ta Valeologiya. 2008;10:120-126. (In Ukrainian).
  16. Kryzhanovskiĭ SA, Vititnova MB. Omega-3 polyunsaturated fatty acids and the cardiovascular system. Fiziol Cheloveka. 2009 Jul-Aug;35(4):110-23. Review. Russian. [pm id"=19799343"]
  17. Zagajko AL, Voronina LM, Kaliman PA, Strelchenko EV. Effect of chronic social stress on lipid metabolism in golden Syrian hamsters. Ukr Biokhim Zhurn. (1999). 2008 Jul-Aug;80(4):120-9. Ukrainian. [pm id="19140458"].
  18. Smolyar V. I. Nutritional effectors of lipid metabolism. Problemy Kharchuvannya. 2003;1:8-14. (In Ukrainian).
  19. Drogomyreczka M. S., Makarenko O. A., Sukmanskyi O. I. Correction of lipid metabolism in rats with alimentary hyperlipidemia. Dentalnye Tekhnologii. 2010;44(1):53-57. (In Ukrainian).
 
Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License.